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 prefrontal cortex



2109737282d2c2de4fc5534be26c9bb6-Paper.pdf

Neural Information Processing Systems

Higher-order brain areas such as the frontal cortices are considered essential for the flexible solution of tasks. However, the precise computational role of these areas is still debated.


Young children's anthropomorphism of an AI chatbot: Brain activation and the role of parent co-presence

arXiv.org Artificial Intelligence

Artificial Intelligence (AI) chatbots powered by a large language model (LLM) are entering young children's learning and play, yet little is known about how young children construe these agents or how such construals relate to engagement. We examined anthropomorphism of a social AI chatbot during collaborative storytelling and asked how children's attributions related to their behavior and prefrontal activation. Children at ages 5-6 (N = 23) completed three storytelling sessions: interacting with (1) an AI chatbot only, (2) a parent only, and (3) the AI and a parent together. After the sessions, children completed an interview assessing anthropomorphism toward both the AI chatbot and the parent. Behavioral engagement was indexed by the conversational turn count (CTC) ratio, and concurrent fNIRS measured oxygenated hemoglobin in bilateral vmPFC and dmPFC regions. Children reported higher anthropomorphism for parents than for the AI chatbot overall, although AI ratings were relatively high for perceptive abilities and epistemic states. Anthropomorphism was not associated with CTC. In the right dmPFC, higher perceptive scores were associated with greater activation during the AI-only condition and with lower activation during the AI+Parent condition. Exploratory analyses indicated that higher dmPFC activation during the AI-only condition correlated with higher end-of-session "scared" mood ratings. Findings suggest that stronger perceptive anthropomorphism can be associated with greater brain activation related to interpreting the AI's mental states, whereas parent co-presence may help some children interpret and regulate novel AI interactions. These results may have design implications for encouraging parent-AI co-use in early childhood.


HIPPD: Brain-Inspired Hierarchical Information Processing for Personality Detection

arXiv.org Artificial Intelligence

Personality detection from text aims to infer an individual's personality traits based on linguistic patterns. However, existing machine learning approaches often struggle to capture contextual information spanning multiple posts and tend to fall short in extracting representative and robust features in semantically sparse environments. This paper presents HIPPD, a brain-inspired framework for personality detection that emulates the hierarchical information processing of the human brain. HIPPD utilises a large language model to simulate the cerebral cortex, enabling global semantic reasoning and deep feature abstraction. A dynamic memory module, modelled after the prefrontal cortex, performs adaptive gating and selective retention of critical features, with all adjustments driven by dopaminergic prediction error feedback. Subsequently, a set of specialised lightweight models, emulating the basal ganglia, are dynamically routed via a strict winner-takes-all mechanism to capture the personality-related patterns they are most proficient at recognising. Extensive experiments on the Kaggle and Pandora datasets demonstrate that HIPPD consistently outperforms state-of-the-art baselines.



Neural Brain: A Neuroscience-inspired Framework for Embodied Agents

arXiv.org Artificial Intelligence

The rapid evolution of artificial intelligence (AI) has shifted from static, data-driven models to dynamic systems capable of perceiving and interacting with real-world environments. Despite advancements in pattern recognition and symbolic reasoning, current AI systems, such as large language models, remain disembodied, unable to physically engage with the world. This limitation has driven the rise of embodied AI, where autonomous agents, such as humanoid robots, must navigate and manipulate unstructured environments with human-like adaptability. At the core of this challenge lies the concept of Neural Brain, a central intelligence system designed to drive embodied agents with human-like adaptability. A Neural Brain must seamlessly integrate multimodal sensing and perception with cognitive capabilities. Achieving this also requires an adaptive memory system and energy-efficient hardware-software co-design, enabling real-time action in dynamic environments. This paper introduces a unified framework for the Neural Brain of embodied agents, addressing two fundamental challenges: (1) defining the core components of Neural Brain and (2) bridging the gap between static AI models and the dynamic adaptability required for real-world deployment. To this end, we propose a biologically inspired architecture that integrates multimodal active sensing, perception-cognition-action function, neuroplasticity-based memory storage and updating, and neuromorphic hardware/software optimization. Furthermore, we also review the latest research on embodied agents across these four aspects and analyze the gap between current AI systems and human intelligence. By synthesizing insights from neuroscience, we outline a roadmap towards the development of generalizable, autonomous agents capable of human-level intelligence in real-world scenarios.


Interpretable Neuropsychiatric Diagnosis via Concept-Guided Graph Neural Networks

arXiv.org Artificial Intelligence

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools. Resting-state functional magnetic resonance imaging (rs-fMRI) provides a powerful lens into large-scale functional connectivity, where brain regions are modeled as nodes and inter-regional synchrony as edges, offering clinically relevant biomarkers for psychiatric disorders. While prior works use graph neural network (GNN) approaches for disorder prediction, they remain complex black-boxes, limiting their reliability and clinical translation. In this work, we propose CONCEPTNEURO, a concept-based diagnosis framework that leverages large language models (LLMs) and neurobiological domain knowledge to automatically generate, filter, and encode interpretable functional connectivity concepts. Each concept is represented as a structured subgraph linking specific brain regions, which are then passed through a concept classifier. Our design ensures predictions through clinically meaningful connectivity patterns, enabling both interpretability and strong predictive performance. Extensive experiments across multiple psychiatric disorder datasets demonstrate that CONCEPTNEURO-augmented GNNs consistently outperform their vanilla counterparts, improving accuracy while providing transparent, clinically aligned explanations. Furthermore, concept analyses highlight disorder-specific connectivity patterns that align with expert knowledge and suggest new hypotheses for future investigation, establishing CONCEPTNEURO as an interpretable, domain-informed framework for psychiatric disorder diagnosis.



THIRDEYE: Cue-Aware Monocular Depth Estimation via Brain-Inspired Multi-Stage Fusion

arXiv.org Artificial Intelligence

Monocular depth estimation methods traditionally train deep models to infer depth directly from RGB pixels. This implicit learning often overlooks explicit monocular cues that the human visual system relies on, such as occlusion boundaries, shading, and perspective. Rather than expecting a network to discover these cues unaided, we present ThirdEye, a cue-aware pipeline that deliberately supplies each cue through specialised, pre-trained, and frozen networks. These cues are fused in a three-stage cortical hierarchy (V1->V2->V3) equipped with a key-value working-memory module that weights them by reliability. An adaptive-bins transformer head then produces a high-resolution disparity map. Because the cue experts are frozen, ThirdEye inherits large amounts of external supervision while requiring only modest fine-tuning. This extended version provides additional architectural detail, neuroscientific motivation, and an expanded experimental protocol; quantitative results will appear in a future revision.


Less is More: some Computational Principles based on Parcimony, and Limitations of Natural Intelligence

arXiv.org Artificial Intelligence

Natural intelligence (NI) consistently achieves more with less. Infants learn language, develop abstract concepts, and acquire sensorimotor skills from sparse data, all within tight neural and energy limits. In contrast, today's AI relies on virtually unlimited computational power, energy, and data to reach high performance. This paper argues that constraints in NI are paradoxically catalysts for efficiency, adaptability, and creativity. We first show how limited neural bandwidth promotes concise codes that still capture complex patterns. Spiking neurons, hierarchical structures, and symbolic-like representations emerge naturally from bandwidth constraints, enabling robust generalization. Next, we discuss chaotic itinerancy, illustrating how the brain transits among transient attractors to flexibly retrieve memories and manage uncertainty. We then highlight reservoir computing, where random projections facilitate rapid generalization from small datasets. Drawing on developmental perspectives, we emphasize how intrinsic motivation, along with responsive social environments, drives infant language learning and discovery of meaning. Such active, embodied processes are largely absent in current AI. Finally, we suggest that adopting 'less is more' principles -- energy constraints, parsimonious architectures, and real-world interaction -- can foster the emergence of more efficient, interpretable, and biologically grounded artificial systems.